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HLH and MAS resources

Educational tools, support organizations, and expert information

Hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS) are serious hyperinflammatory conditions that may progress quickly and can be difficult to recognize. Because signs and symptoms may overlap with infection, malignancy, autoimmune disease, and other inflammatory conditions, timely education and access to reliable information are important for patients, caregivers, and healthcare professionals.

This page brings together educational materials and downloadable resources for healthcare professionals, patients, and caregivers who would like to learn more about HLH and MAS.

Downloadable resources

To quickly sort through the available resources, use the filter below.

HLH Disease Mimic: Sepsis

This high-level flash card for healthcare professionals outlines some of the key differences between HLH and sepsis—2 conditions that may present similarly in patients.

Download
The Dragon Inside: A Family Guide to Understanding HLH

The Dragon Book is a guide for patients and their caregivers that explains HLH in a way that is child-friendly. It also contains more in-depth information for caregivers who would like to have a deeper understanding of HLH.

Download
HLH and MAS Mechanism of Disease Video
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Watch a short video explaining how IFNγ drives dangerous hyperinflammation in HLH 
and MAS.